Uncombable Hair Syndrome

Pili trianguli et canaliculi is a rare genetic disease also known as "uncombable hair syndrome" and "spun glass hair." From an abstract in the medical journal Ultrastructural Pathology (photo from The World's Fair blog):
 3172 2612405338 0F265Fc152 Both inherited (autosomal dominant and recessive with variable levels of penetrance) and sporadic forms of uncombable hair syndrome have been described, both being characterized by scalp hair that is impossible to comb due to the haphazard arrangement of the hair bundles. A characteristic morphologic feature of hair in this syndrome is a triangular to reniform to heart shape on cross-sections, and a groove, canal or flattening along the entire length of the hair in at least 50% of hairs examined by scanning electron microscopy. Most individuals are affected early in childhood and the hair takes on a spun-glass appearance with the hair becoming dry, curly, glossy, lighter in color, and progressively uncombable. Only the scalp hair is affected.
Uncombable Hair Sydrome on Wikipedia, Uncombable Hair Syndrome on The World's Fair blog

Discussion

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Rod Stewart turned it into an asset.

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#2 posted by EH, June 26, 2008 10:59 AM

typo in "spung."

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It seems this disease is rather inaccurately named. The hair is comable, it simply won't stay that way. When I read the title I got the impression that the disease would create a solid mass of hair, which would be indeed, uncomable. Or combable. Whichever is correct.

The pic looks like hair that has been overbleached - exact same texture.

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That looks like albino Hulk hair. Lou Ferrigno style.

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Emo-Hair Syndrome.

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Boris-Head Syndrome

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If I have this, can I apply for social security benefits?

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#10 posted by Tavie, June 26, 2008 1:03 PM

What's the syndrome where your hair looks messy five minutes after you comb it?

I gots that.

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What happens if you use conditioner?

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Wow- finally a name for a disease I've suffered from for most of my life... I wonder if I can get some form of disability benefit? :)

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What about black rectangle over eyes syndrome?

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BADKITTYM: Yeah, 2nd on the hair looking bleached. That's what my hair looks like after I bleach it. Weird, it kind of behaves in a similar way right after stripping all the color out. It stands straight up from my scalp.

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Christopher Walken would surely fall into this category...no?

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What if you let it grow out? Is the hair resistant to some of the stronger gels and styling projects? What about having it blown or something at a salon? Is there really nothing which can be done? I guess I kinda feel bad complaining about my own (controllable though erratic) hair texture now.

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How is there only one picture of this? And it looks like someone with s----y 80s hair, not some crazy obscure malady. I'm calling Long Horse.

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#18 posted by Slea, June 26, 2008 4:05 PM

There a good link (with more pictures) here.

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#16 - actually, these days it's kinda nifty to have hair that is uncontrollable. A good cut, a little texturizer, and voila! As a person whose hair has a mind of its own and always has, I LIKE my Irish Afro. I had big hair before it was in, and big hair after it was out again. Only during the late seventies and part of the eighties did most everyone look (or try to look) the same as I did, hair-wise. My advantage was not needing to use an entire can of Aquanet to achieve the gravity-defying styles of the times.

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#20 posted by Fnarf, June 26, 2008 4:59 PM

This is different than white-girl Trustafarian dreadlocks, right?

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Judging by the photo, uncombable hair syndrome also causes unbridled joy.

That is without doubt the happiest I've ever seen someone who's had their eyes blacked out. Sounds like a fun idea for an art project — anonymous glee.

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Ooooh! Ooooh! I know two kids with this kind of hair. At least, I think this is what they have. They are exQUISite, with fine, perfect features and absolute THATCHES of this hair, sort of dusky blonde. They look like elfin children or something. They are otherworldly-looking. I always want to touch their hair. Some day I'm gonna cop a feel very casually. Actually, I'd like to pluck a few strands and get a look at a cross-section.

But really, I'm no a danger to children. Really.

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#10
It's called "moose & gel deficiency"

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Hmmm ... judging from the pictures, yes, this is truly crazy - the hair really does look like fibreglass, or look they put wet gel in and went to sleep on it as it dried.


And while we're on links to OMIM, here's my favourite hereditary "disorder": Autosomal Dominant Compelling Helioopthalmic Outburst Syndrome (ACHOO) - sneezing on sudden exposure to bright sunlight. (I have this, as, it would seem, do quite a lot of people) :)

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#26 posted by acx99, June 27, 2008 5:07 AM

Does the syndrome also cause you to have gaping rectilinear holes where your eyes should be?

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A tin of Murray's pomade would clear that condition right up. Make it combable, but then ummovable.

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Does this explain Nick Nolte's mug shot from a few years back?

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And why hasn't our pharmaceutical industry come up with a pill for this... syndrome... yet?

"FolliclEaz" or somesuch?

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This seems to explain Andy Warhol's hair, tho' not why his wig was similarly designed.

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My youngest son has the same kind of hair. He keeps it short but it is really soft. It is light blond with traces of red in it. It has a shimmer to it in the light. Conditioners don't do a thing. Gels work but only if you slather it on and basically glue the hair in place. When he was little we let it grow, It would almost stick out straight for more than 3 inches. No one else in the family has it.

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#32 posted by Alli, June 28, 2008 7:29 PM

Look up UNCOMBABLE HAIR on http://dermatlas.med.jhmi.edu/derm/ ; there's a ton of pics and info including microscopic views. Oh, and you may not wish to look up much else - it's a pretty graphic site and not for the weak stomached.

Alli

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Did someone ask for a derm horror story? Okay. So we had this patient with bullous pemphigus (don't look it up) which caused a lot of her skin to slough off, to the point where you could see her back ribs, see the actual bone. The area was covered with one of those clear dressings that looks like breathable saran wrap. Unfortunately, she was in the room next to the pantry. One morning, when the nurse went to change her dressing, there were hundreds of ants under it, eating her flesh while she lay in her hospital bed. Seriously, don't get sick.

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#34 posted by izzzzy, June 29, 2008 3:43 AM

My son has these "cowlicks" all over his head. They are uncombable,so we just keep it short.

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#35 posted by dora_k, June 30, 2008 1:57 AM

I think one of my barbies when I was a kid had this condition.

Antinous, thanks -- not eating anything ever again will surely be good for my figure.

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#36 posted by Anonymous, May 23, 2009 8:38 AM

Doc Tourneau, This is a rare genodermatosis genetic disorder. The pharmaceutical industry can't create a pill to fix genes, chromosomes, and dna. That's like asking why we don't have a pill to change eye color, hair color, skin color, our sex, our height... get the point. (Unless you possess the ability to attempt this miraculous feat?) Godspeed, Jewel

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